Uterine Cancer Can Be Indicator for Other Cancers

Uterine cancer patients have an increased risk of contracting colon, ovarian and gastric cancers says a study just published by the Ohio State University Comprehensive Cancer Center. A study of 543 women showed that about one in 50 women with uterine cancer have a mutation, called Lynch syndrome, that links the cancers.

Because uterine cancer carries a fairly decent prognosis, women with Lynch syndrome "are probably going to go on to survive their endometrial cancer and sadly go on to get colon cancer," said Heather Hampel, a genetic counselor at OSU and lead author of the study.

As reported in the Columbus Dispatch, the OSU study is the first comprehensive screening for Lynch syndrome in a large number of women with uterine cancer (click the post title to read the article). Children have a 50% chance of inheriting the mutation from a parent. Aggressive screening beginning in the mid-20s is recommended for women found to have Lynch syndrome and study leaders recommend that family members be tested for the genetic link.

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